* Based on a consumer questionnaire from an in vivo study using a serum containing 3% CutiFine CLR™. 23 female participants aged 45–65 were asked whether they agreed with the statement: “My facial pores are less visible” after 28 and 56 days of use.
Eiben-Nielson et al., Development and validation of a global photonumeric scale for evaluating skin quality of aged female facial skin, J Cosmet Dermatol 2021 Dec;20(12):4032–4039. doi: 10.1111/jocd.14058. Epub 2021 Mar 24.
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NEW
Biofemage® range by Aesthetics Rx®
A New Era in Skincare formulated for visible signs of mature skin.
What if your skincare could evolve with you, comforting changing skin, helping restore glow, resilience and hydration at every life stage.
Meet Biofemage® skincare that finally gets your drier, thinner, more sensitised skin from age 45 and beyond.
A mature skin reboot
Biofemage® Serum
This isn’t your traditional anti-ageing serum.
Biofemage® Serum is a high-potency formula that understands the underlying causes of hormonally driven skin changes – from cellular slowdown to collagen loss.
What it does:
- Helps restore visible firmness and bounce with skin-supportive biotech actives
- Smooths texture and refines tone for a more radiant, even-looking complexion
- Strengthens the skin barrier for improved visible hydration and resilience
Hero ingredients:
- Cellynkage™ – biotech marine extract to visibly improve skin firmness••
- CutiFine CLR™ – clinically shown to visibly reduce pore appearance and improve skin texture*
- Niacinamide + Arbutin – visibly brighten and even out tone
- Multi-weight Hyaluronic Acid – hydrates and visibly plumps
Myristoyl Tripeptide‐31 – a gentle, retinoid-like peptide that improves the appearance of skin firmness and resilience
- Botanical phytoestrogens – Red Clover, Pomegranate, Yam, and Black Cohosh
Your all-in-one solution for hydration, repair and comfort
Biofemage® Cream
This nourishing moisturiser works alongside the serum to visibly soothe, hydrate and support firmer-looking, hormonally shifting skin.
What it does:
- Formulated with 5% Cellynkage™, shown to visibly improve skin smoothness and firmness in just 28 days**
- Helps improve visible skin sagging and wrinkles after 28 days***
- Assists in enhancing the appearance of skin’s smoothness and even skin tone, as observed in clinical trials on mature skin**
- Promotes a visibly healthier and more even complexion, helping skin appear more balanced and radiant**
Hero ingredients:
- Multi-weight Hyaluronic Acid – visibly plumps and hydrates
- Red Clover Extract – rich in isoflavones and antioxidants
- Botanical complex – Pomegranate, Yam, Black Cohosh, and Jujube
- Baobab (Adansonia Digitata) Extract – rich in essential fatty acids
- Niacinamide – helps visibly brighten and strengthen the skin barrier
- Myristoyl Tripeptide‐31 – improves visible firmness and elasticity
- Cellynkage™ – marine-derived biotech active that improves the appearance of a more youthful radiant skin
- Phytogen – plant-based active for visibly reducing wrinkle depth and length****
Clinical Support & References
Biofemage® Serum
Biofemage® Cream
** Based on a 28-day in vivo consumer study by Lubrizol Advanced Materials, Inc. using 5% Cellynkage™ marine ingredient, with women aged 50–65.
*** Based on a 56-day instrumental in vivo study by Lubrizol Advanced Materials, Inc. using 2% Cellynkage™ on hormonally aged skin.
**** Based on an 8-week in vivo study with 21 women aged 45–65 using a cream containing 2% Phytogen.
Test Instruments: Elasticity: MPA 580 (CK Electronic GmbH, Germany), Wrinkle depth and length: SILFLO (CuDerm, USA), Visioline VL650 (CK Electronic GmbH).
Treatments + Skincare
Support and rejuvenates hormonally aged skin from ages 45 and beyond.
Prices are subject to change without prior notice. Terms and conditions may apply.
Radiance at Every Stage: How to Care for Your Skin Through Menopause
There’s a moment many of us reach when we notice our skin is changing in ways we didn’t expect. It might feel drier, more sensitive, or a little less luminous than it used to be. Patches of pigmentation can appear, and those fine lines suddenly seem deeper. If this feels familiar, you’re not alone.
Perimenopause & Your Skin: What You Need to Know
Perimenopause is a time of enormous change, yet many women find themselves unprepared for what it truly entails, especially when it comes to the skin. While hot flushes and mood changes are well-known, the perimenopause skin changes that show up on your face and body can be just as impactful.
Pigmentation in your 40s hits different. Here’s what an expert wants you to know.
From your 40s onwards, it can feel like the rules suddenly changed — and no one gave you the memo. Especially when it comes to your skin.
One minute you’re cruising through your skin routine with a basic moisturiser and the next you’re noticing changes in tone and texture that weren’t there before.
