Total Repair DNA Serum

This product is only to be used at night.

After cleansing at night, dispense 1-3 drops to the fingertips and smooth over the face and neck until absorbed, avoiding the eye contour. Follow with Aesthetics Rx moisturiser and/or facial oil to complete the nightly regime.

If discomfort occurs, rinse with warm water. For external use only.

Store below 25 ̊C.

Are there any precautions?

This serum is designed to speed up cell renewal. It can make your skin more photo (sun) sensitive than usual. You must use SPF50+ during the day, every day, but especially when you are using this product, or any Vitamin A based product.

We also recommend wearing a sunhat if you are going to be exposed to the sun.

It is recommended to cease other treatments (facial waxing, microdermabrasion, chemical peels and laser treatments) whilst using this product and for at least 3 days before having one of these treatments, and 7 days after one of those treatments.

It is recommended not to use this or any Vitamin A products when you are pregnant. If you started using the product, or a Vitamin A based product before you realised you were pregnant, it ok! Just cease using the product/s until after the birth of your baby and you’ve finished breastfeeding.

We recommend if you are using a C Serum, you use the Vitamin C serum during the day and use the Vitamin A serum, including Total Repair DNA Serum at night. Don’t use them together.

If you happen to experience a response that is more than just mild, we recommend ceasing use immediately. Cool water compress is the best way to manage discomfort, irritation or redness in this instance.

It can be useful to cease using other active products like Glycolic acids, Lactic acids, Salicylic acids and Enzyme peels when you are using this product. Don’t use other Vitamin A based products while you are using this product.

We recommend not using Ultimate Serum, A Serum or A Serum 1% whilst you are using Total Repair DNA Serum. And, many skins will benefit from using this product sparingly, at the rate of 1 -3 nights per week only, particularly as the skin may take time to tolerate it.

Key active ingredients:

Hexapeptide – Biomimetic peptide that improves the skins natural DNA repair pathways, enhances cellular longevity and vitality. Protects and prevents DNA damage from UV light and pollution.

Hyaluronic acid – high and low molecular weight Hyaluronic acid to provide immediate and long-lasting hydration, with additional collagen boosting and cellular cohesion benefits.

Epidermal Growth Factor – a completely vegan active, that contains five different growth factors (IGF-1, EGF, acidic FGF, basic FGF, and VEGF), amino acids and vitamins. The growth factors in our serum are obtained safely through a microbial fermentation process, biotechnology.

Total Repair DNA is our most sophisticated and potent serum yet, formulated to offer visual anti-ageing skin benefits. We use this material to visibly promote the look of a healthier complexion and smooth the appearance of fine lines and wrinkles.

Lipochroman Molecule – superb triple antioxidant and protective shield against pollution and oxidative stress. Prevents skin damage by RNS, ROS and RCS, activates detoxification.

Retinal – Retinal is a completely natural Retinoic acid precursor, one conversion step away from Retinoic acid (the metabolised retinoid form that the skin can use) versus a two-step conversion away for Retinol. Retinal has a more controlled delivery at a cellular level when compared to Retinol, resulting in fewer adverse effects. Retinal is clinically proven to be a more stable retinoid with enhanced skin tolerability compared to Retinol. Proven topical agent for the treatment of prematurely aged skin, photoaged skin and for the treatment of acne and mild Rosacea. Increases skin elasticity, protects against free radical damage, increases dermal density, reduces the appearance of lines and wrinkles, smooths skin, reduces hyperpigmentation. With antibacterial properties Retinal may improve signs of acne. Improves the appearance of vascularisation and redness.

Micro algae and Polysaccharide complex – biotechnologically produced extract from the microalgae Nannochloropsis oculate, combined with a well-balanced fraction of polysaccharides– provides instant tightening effect and long-term skin firming benefits.

Seabuckthorn Oil – nourishing oil rich in essential fatty acids and exceptional antioxidant benefits. Contains Linoleic acid (also found in the skins natural sebum) which helps regulate hydration and balances oil on the skins surface. Anti-bacterial and anti-fungal properties.

Full ingredients list:

Aqua (Water), Shea Butter Ethyl Esters, Propanediol, Brassica Glycerides, Butylene Glycol, Glyceryl Stearate SE, Behenyl Alcohol, Phenoxyethanol, Glycerin, Sodium Acrylates Copolymer, Pullulan, Hydrolyzed Hyaluronic Acid, Butyrospermum Parkii (Shea) Butter, Lecithin, Sodium Hyaluronate, Lysolecithin, Sclerotium Gum, Nannochloropsis Oculata Extract, Hippophae Rhamnoides (Seabuckthorn) Fruit Oil, Disodium EDTA, Sodium Hydroxymethylglycinate, Retinal, Ethyhexylglycerin, Pentylene Glycol, Tocopherol, Dimethylmethoxy Chromanol, Xanthan Gum, Acetyl Glutamine, Glycine Soja (Soybean) Oil, Bacillus/Folic Acid Ferment Filtrate Extract, Caprylyl Glycol, 1,2-Hexanediol, Acetyl Hexapeptide-51 Amide, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, sh-Polypeptide-11, Citric Acid.

Total Repair DNA Serum delivers synchronised recovery, repair, and rejuvenating skin benefits, optimising the restorative functions of night-time rest. Between the hours of 11pm and 4am when skin daytime protective functions have completely wound down, the natural release of hormones including Melatonin and the Human Growth Hormone (HGH) amplify skin repair and cell regeneration functions while the body is at sleep. The ingredients selected for our most advanced formula, support and enhance this renewal process. Additional actives trigger moisture replenishment and skin barrier repair which is usually under environmental attack throughout the day. Detoxification is activated by components in this complex, incorporated to counteract ROS, RNS and RCS damage, when DNA repair is at its peak overnight.

In vivo clinical studies performed at the Korea Institute for Skin and Clinical Sciences on women between the ages of 43 to 50 (average age : 45.75) using a 3% input of the epidermal growth factors in a cream over 4 weeks delivered the following results:

• Reduced wrinkles by 13% in 2 weeks and 16% in 4 weeks on crow’s feet
• Reduced wrinkles by 38% in 2 weeks and 46% in 4 weeks on below eyes
• Reduced wrinkles by 10% in 2 weeks and 21% in 4 weeks on crow’s feet
• Skin elasticity improved by 32% in 2 weeks and 47% in 4 weeks
• Skin Moisturising improved by 83% just after applying, 50% in 2 weeks and 64% in 4 weeks

*Aesthetics Rx® Total Repair DNA Serum contains 3% of the EGF.